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Our team


Professor Karen Barnes
CCOAT Founding Director & Principal Investigator

Professor, UCT Division of Clinical Pharmacology

Director, Worldwide Antimalarial Resistance Network (WWARN) Pharmacology


Tel:+27 21 4066294


Dr. Elizabeth Allen

Head of Clinical Research

Scientific Coordinator WWARN

Coordinator, Global Health Trials South Africa, Global Pharmacovigilance


Tel: +27 21 6504070


Dr. Phumla Sinxadi

Lead Investigator

Senior Lecturer,UCT Division of Clinical Pharmacology


Tel:+27 21 650-4096


Mrs. Lesley Workman

Senior Data Manager

WWARN Pharmacology Scientific Coordinator


Tel:+27 21 650-4077


Mr Aaron Mabuza

Project Coordinator, malaria field studies and elimination activities




Mrs Faikah Davids

Clinical Research Assistant


Tel: +27 21 406-6996

Dr Elize Pietersen

Project Coordinator, Global Research Nurses





For our clinical trials we work closely with the UCT Clinical Research Centre, which has a 24 bed Phase 1 ward

Key Collaborating Centre members include:


Prof Kelly Chibale

Founding Director, H3-D; DST/NRF SARChI

Chair in Drug Discovery Department of Chemistry

University of Cape Town


Prof Lucille Blumberg 

Deputy Director 

National Institute for Communicable Diseases 

National Health Laboratory Service


A/Prof Francesca Little 

Head of the Department of Statistical Sciences 

University of Cape Town

Other collaborators include:


Dr Jaishree Raman

Senior Scientist  

National Institute of Communicable Diseases


Dr Ushma Mehta

Independent Pharmacovigilance Consultant 


Philip Kruger

Programme Manager

Provincial Malaria Control Program, 

Limpopo Province


Dr Lubbe Wiesner

Senior Lecturer  

Bioanalytical Laboratory, Division of Clinical Pharmacology  

University of Cape Town


Dr Paolo Denti 

Associate Professor  

Head of Pharmacometrics, Division of Clinical Pharmacology 

University of Cape Town